Determination of finerenone – a novel, selective, nonsteroidal mineralocorticoid receptor antagonist – in human plasma by high-performance liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study in venous and capillary human plasma
Gabriele Rohde, Stephanie Loewen, Roland Heinig
Topics & Concepts
ChromatographyProtein precipitationChemistryPharmacokineticsTandem mass spectrometryHigh-performance liquid chromatographyDetection limitMass spectrometryPharmacologyMedicineHormonal Regulation and HypertensionIon Transport and Channel RegulationHormonal and reproductive studies