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Synthesis and structure-activity relationship of new chalcone linked 5-phenyl-3-isoxazolecarboxylic acid methyl esters potentially active against drug resistant Mycobacterium tuberculosis

Santosh K. Sahoo, Bandela Rani, Nikhil Baliram Gaikwad, Mohammad Naiyaz Ahmad, Grace Kaul, Manjulika Shukla, Srinivas Nanduri, Arunava Dasgupta, Sidharth Chopra, Venkata Madhavi Yaddanapudi

2021European Journal of Medicinal Chemistry25 citationsDOI

Topics & Concepts

AntimycobacterialMycobacterium tuberculosisChemistryChalconeMinimum inhibitory concentrationTuberculosisVero cellIn vitroMycobacteriumIsoniazidAntimicrobialStereochemistryMicrobiologyBiochemistryBiologyOrganic chemistryPathologyMedicineSynthesis and biological activityQuinazolinone synthesis and applicationsSynthesis and Biological Evaluation
Synthesis and structure-activity relationship of new chalcone linked 5-phenyl-3-isoxazolecarboxylic acid methyl esters potentially active against drug resistant Mycobacterium tuberculosis | Litcius