Phosphorus–nitrogen compounds. Part 64. Comparative reactions of spiro and ansa (N/O) cyclotetraphosphazenes with bulky (4-fluorobenzyl) N/N and N/O donor type bidentate reagents: structure, stereogenic properties and cytotoxic activity studies
Gamze Elmas, Arzu Binici, Mehtap Yakut, Aytuğ Okumuş, Zeynel Kılıç, Bünyemin Çoşut, Tuncer Hökelek, Nebahat Aytuna Çerçi, Leyla Açık
Abstract
Novel inorganic–organic hybrid multiheterocyclic-spiro and ansa cyclotetraphosphazenes were synthesized. The spectral, crystallographic, and stereogenic properties, and the cytotoxic activities of the compounds were presented.
Topics & Concepts
ChemistryStereocenterReagentCytotoxic T cellNitrogenPhosphorusDenticityStereochemistryOrganic chemistryEnantioselective synthesisCrystal structureIn vitroBiochemistryCatalysisOrganophosphorus compounds synthesisSynthesis and Reactivity of Sulfur-Containing CompoundsSynthesis of Organic Compounds