Drug antagonism and single-agent dominance result from differences in death kinetics
Ryan Richards, Hannah Schwartz, Megan E. Honeywell, Mariah Stewart, Peter Cruz‐Gordillo, Anna J. Joyce, Benjamin Landry, Michael J. Lee
Topics & Concepts
AntagonismDrugDominance (genetics)Programmed cell deathCrosstalkBiologyApoptosisPharmacologyGeneticsReceptorGeneOpticsPhysicsPARP inhibition in cancer therapyComputational Drug Discovery MethodsProtein Structure and Dynamics