CRISPR screen in cancer: status quo and future perspectives.
Chenglong He, Siqi Han, Yue Chang, Meijuan Wu, Yulu Zhao, Cheng Chen, Xiaoyuan Chu
Abstract
, with a particular focus on identifying cancer immunotherapy targets, and propose optimizing strategies and future perspectives for CRISPR screen.
Topics & Concepts
CRISPRGenome editingComputational biologyTrans-activating crRNACarcinogenesisBiologyGenomeGeneTumor microenvironmentCancer immunotherapyCancer researchCancerImmunotherapyGeneticsCRISPR and Genetic EngineeringCAR-T cell therapy researchCancer Mechanisms and Therapy