<i>In situ</i> formation of transcriptional modulators using non-canonical DNA i-motifs
Puja Saha, Deepanjan Panda, Diana Müller, Arunabha Maity, Harald Schwalbe, Jyotirmayee Dash
Abstract
Herein, i-motif DNA-immobilized magnetic nanoparticles are used as templates to promote the <italic>in situ</italic> cycloaddition generating specific binders for i-motifs.
Topics & Concepts
DNAG-quadruplexChemistryStructural motifSequence motifGeneComputational biologyBiologyBiochemistryAdvanced biosensing and bioanalysis techniquesDNA and Nucleic Acid ChemistryRNA Interference and Gene Delivery