Inhibition of thioredoxin reductase 1 correlates with platinum-based chemotherapeutic induced tissue injury
Ping Chen, Huan Liu, Yinchuan Li, Peiling Pi, Yu Jiang, Shaozhen Zang, Xiaorong Li, Ailing Fu, Xiaoyuan Ren, Jianqiang Xu, Arne Holmgren, Jun Lu
Topics & Concepts
CisplatinThioredoxin reductaseCarboplatinOxaliplatinPharmacologyNephrotoxicityChemistryThioredoxinAntioxidantOxidative stressKidneyBiochemistryCancer researchBiologyMedicineChemotherapyCancerInternal medicineEndocrinologyColorectal cancerGlutathione Transferases and PolymorphismsSelenium in Biological SystemsMetal complexes synthesis and properties