Distinct small non-coding RNA landscape in the axons and released extracellular vesicles of developing primary cortical neurons and the axoplasm of adult nerves
Raquel Mesquita-Ribeiro, Rafael Sebastián Fort, Alex Rathbone, Joaquina Farías, Cristiano Lucci, Victoria James, José Sotelo‐Silveira, Marı́a Ana Duhagon, Federico Dajas‐Bailador
Abstract
.The existence of these complex sncRNA populations that are specific to distinct neuronal subdomains and selectively incorporated into EVs, equip neurons with key molecular tools for spatiotemporal functional control and cell-to-cell communication.
Topics & Concepts
BiologymicroRNARNANon-coding RNACell biologyAxoplasmNeuroscienceTransfer RNAGeneAxonGeneticsCancer-related molecular mechanisms researchRNA Research and SplicingRNA modifications and cancer