HIV and SARS-CoV-2 co-infection: The diagnostic challenges of dual pandemics
Arifa Parker, Jane Shaw, Sumanth Karamchand, Sa’ad Lahri, Neshaad Schrueder, M-Y Chothia, Abdurasiet Mowlana, Usha Lalla, Brian Allwood, Coenraad F.N. Koegelenberg, Jantjie Taljaard
Abstract
The first critically ill patient admitted to our hospital in Cape Town, South Africa, during the COVID-19 pandemic was co-infected with HIV and SARS-CoV-2. Pneumocystis jirovecii pneumonia (PCP) and other respiratory opportunistic infections share many clinical features with severe COVID-19. Our understanding of the nuances of co-management of HIV and COVID-19 is evolving. We describe the diagnostic and therapeutic challenges presented by this case.
Topics & Concepts
MedicinePandemicPneumoniaCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Intensive care medicinePneumocystis jiroveciiHuman immunodeficiency virus (HIV)2019-20 coronavirus outbreakCritically illAIDS-Related Opportunistic InfectionsVirologySidaViral diseaseInfectious disease (medical specialty)PathologyDiseaseInternal medicineOutbreakPneumocystis jirovecii pneumonia detection and treatmentTuberculosis Research and EpidemiologyPneumonia and Respiratory Infections