Regulation of extrinsic apoptotic signaling by c-FLIP: towards targeting cancer networks
Nikita V. Ivanisenko, Kamil Seyrek, Laura K. Hillert-Richter, Corinna König, Johannes Espe, Kakoli Bose, Inna N. Lavrik
Topics & Concepts
NecroptosisFlipPyroptosisRegulatorApoptosisCell biologyCancer cellSignal transductionCancerCancer researchCarcinogenesisGene isoformCaspase 8BiologyChemistryProgrammed cell deathCaspaseGeneBiochemistryGeneticsCell death mechanisms and regulationCancer-related Molecular PathwaysPARP inhibition in cancer therapy