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Pyrimidine-based EGFR TK inhibitors in targeted cancer therapy

Adileh Ayati, Setareh Moghimi, Mahsa Toolabi, Alireza Foroumadi

2021European Journal of Medicinal Chemistry102 citationsDOIOpen Access PDF

Topics & Concepts

Tyrosine kinaseEGFR inhibitorsTargeted therapyChemistryCancerProtein kinase domainCombination therapyEpidermal growth factor receptorErlotinibCancer researchCancer therapyEpigeneticsPharmacologySignal transductionMedicineBiochemistryInternal medicineGeneMutantLung Cancer Treatments and MutationsHER2/EGFR in Cancer ResearchCancer therapeutics and mechanisms
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