Boosting the performance of an iontophoretic biosensing system with a graphene aerogel and Prussian blue for highly sensitive and noninvasive glucose monitoring
Xiao Li, Tong Li, Baoyang Liu, Ning Hu, Tao Hu, Zhonghua Ni
Abstract
model were developed to demonstrate the efficacy of ISF extraction based on reverse iontophoresis technology. Highly sensitive and accurate detection of ISF glucose could be achieved with an LOD of 0.26 mM over a 0-15 mM range. Finally, tests on healthy volunteers were conducted to further validate the feasibility of this as-proposed system. Combined with its well flexible and biocompatible features, it holds considerable prospects in the development of wireless wearable biosensors for continuous blood glucose monitoring.
Topics & Concepts
Prussian blueIontophoresisBiosensorGrapheneAerogelNanotechnologyMaterials scienceBoosting (machine learning)ChemistryComputer scienceMedicineElectrodeElectrochemistryPhysical chemistryRadiologyMachine learningElectrochemical sensors and biosensorsBiosensors and Analytical DetectionAdvanced biosensing and bioanalysis techniques