Ganoderic acid A exerted antidepressant-like action through FXR modulated NLRP3 inflammasome and synaptic activity
Hongkun Bao, Haoran Li, Yue Jia, Yuhuan Xiao, Shaolei Luo, Dandan Zhang, Li Han, Lili Dai, Chunjie Xiao, Lei Feng, Yuan Feng, Yang Yang, Han Wang, Gang Wang, Jing Du
Topics & Concepts
Farnesoid X receptorAntidepressantInflammasomeG protein-coupled bile acid receptorMajor depressive disorderReceptorPharmacologyBehavioural despair testInternal medicineEndocrinologyNeuroscienceHippocampusChemistryMedicineBiologyNuclear receptorBiochemistryAmygdalaGeneTranscription factorTryptophan and brain disordersStress Responses and CortisolMaternal Mental Health During Pregnancy and Postpartum