Spontaneous Mutational Patterns and Novel Mutations for Delamanid Resistance in Mycobacterium tuberculosis
Yuanyuan Liu, Jin Shi, Lu Li, Tuoya Wu, Ping Chu, Yu Pang, Yongli Guo, Mengqiu Gao, Jie Lu
Abstract
spontaneous DLM-resistance patterns of different clinical strains, which could improve the understanding of the causes of DLM resistance in clinical strains and of the effects on drug resistance of different mutations in genes that are related to the DLM activation pathway.
Topics & Concepts
Mycobacterium tuberculosisTuberculosisDrug resistanceMedicineMultiple drug resistanceBedaquilineExtensively drug-resistant tuberculosisDrugIntensive care medicineMicrobiologyBiologyVirologyPharmacologyPathologyTuberculosis Research and EpidemiologyMycobacterium research and diagnosisCancer therapeutics and mechanisms