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Leptin induces NAFLD progression through infiltrated CD8+ T lymphocytes mediating pyroptotic-like cell death of hepatocytes and macrophages

Qinghui Zhang, Jianjun Wang, Feng Huang, Yongliang Yao, Ling Xu

2020Digestive and Liver Disease35 citationsDOI

Topics & Concepts

PyroptosisLeptinMedicineImmune systemCD8Nonalcoholic fatty liver diseaseHepatocyteFatty liverImmunologyInflammationInflammasomeCancer researchInternal medicineBiologyDiseaseObesityBiochemistryIn vitroLiver Disease Diagnosis and TreatmentRegulation of Appetite and ObesityDiabetes and associated disorders
Leptin induces NAFLD progression through infiltrated CD8+ T lymphocytes mediating pyroptotic-like cell death of hepatocytes and macrophages | Litcius