Single-cell analysis of embryoids reveals lineage diversification roadmaps of early human development
Yi Zheng, Robin Zhexuan Yan, Shiyu Sun, Mutsumi Kobayashi, Lifeng Xiang, Ran Yang, Alexander Goedel, Yu Kang, Xufeng Xue, Sajedeh Nasr Esfahani, Yue Liu, Agnes M. Resto Irizarry, Weisheng Wu, Yunxiu Li, Weizhi Ji, Yuyu Niu, Kenneth R. Chien, Tianqing Li, Toshi Shioda, Jianping Fu
Topics & Concepts
BiologyEpiblastTranscriptomeMesodermPrimitive streakGerm layerBlastocystEctodermCell biologyEmbryoEmbryoid bodyNodal signalingInduced pluripotent stem cellNODALGeneticsGastrulationEmbryogenesisEmbryonic stem cellGene expressionGenePluripotent Stem Cells ResearchSingle-cell and spatial transcriptomicsCRISPR and Genetic Engineering