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<i>Orientia</i> <i>tsutsugamushi</i> Antibodies in Patients with Eschars and Suspected Tickborne Disease

Haley Abernathy, Lauryn Ursery, Brooke A Merdjane, Dana Giandomenico, Ross M. Boyce

2025Emerging infectious diseases6 citationsDOIOpen Access PDF

Abstract

To investigate local transmission of Orientia tsutsugamushi by chiggers in North Carolina, USA, we tested remnant serum specimens from patients with eschar undergoing testing for suspected tickborne disease. We identified 11 persons with O. tsutsugamushi antibodies, including 4 who were positive by both assays; none had severe clinical manifestations consistent with scrub typhus.

Topics & Concepts

EscharOrientia tsutsugamushiMedicineDiseaseAntibodyTransmission (telecommunications)Scrub typhusTick-borne diseaseDermatologyRickettsiosisVirologyImmunologyAntibody responseAntibody titerPathologyTickEpidemiologyVector-borne infectious diseasesComplement system in diseasesParasites and Host Interactions
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