Dose adjustment of venetoclax when co-administered with posaconazole: clinical drug–drug interaction predictions using a PBPK approach
Sumit Bhatnagar, Dwaipayan Mukherjee, Ahmed Hamed Salem, Dale Miles, Rajeev Menon, John P. Gibbs
Topics & Concepts
PosaconazoleVenetoclaxDrugPharmacologyPharmacokineticsMedicinePhysiologically based pharmacokinetic modellingOncologyInternal medicineLeukemiaAntifungalDermatologyAmphotericin BChronic lymphocytic leukemiaChronic Lymphocytic Leukemia ResearchCancer Treatment and PharmacologyCancer therapeutics and mechanisms