Deletion of the H108R Gene Reduces Virulence of the Pandemic Eurasia Strain of African Swine Fever Virus with Surviving Animals Being Protected against Virulent Challenge
Elizabeth A. Vuono, Elizabeth Ramírez-Medina, Ediane Silva, Ayushi Rai, Sarah Pruitt, Nallely Espinoza, Alyssa Valladares, Lauro Velázquez-Salinas, Douglas P. Gladue, Manuel V. Borca
Abstract
Currently, there is no commercial vaccine available to prevent ASF. ASFV-Georgia2007 (ASFV-G) and its field isolate derivatives are producing a large pandemic which is drastically affecting pork production in Eurasia.
Topics & Concepts
BiologyVirulenceVirologyPandemicStrain (injury)VirusVirus strainAfrican swine fever virusGeneMicrobiologyCoronavirus disease 2019 (COVID-19)GeneticsInfectious disease (medical specialty)MedicineAnatomyPathologyDiseaseAnimal Disease Management and EpidemiologyVector-Borne Animal DiseasesViral gastroenteritis research and epidemiology