The measurement properties of tests and tools used in cystic fibrosis studies: a systematic review
Charlie McLeod, Jamie Wood, Allison Tong, André Schultz, Richard Norman, Sherie Smith, Christopher C. Blyth, Steve Webb, Alan R Smyth, Tom Snelling
Abstract
There is no consensus on how best to measure responses to interventions among children and adults with cystic fibrosis (CF). We have systematically reviewed and summarised the characteristics and measurement properties of tests and tools that have been used to capture outcomes in studies among people with CF, including their reliability, validity and responsiveness. This review is intended to guide researchers when selecting tests or tools for measuring treatment effects in CF trials. A consensus set of these tests and tools could improve consistency in how outcomes are captured and thereby facilitate comparisons and synthesis of evidence across studies.