Endothelialization of an ePTFE vessel prosthesis modified with an antithrombogenic fibrin/heparin coating enriched with bound growth factors
Johanka Táborská, Zuzana Reicheltová, Eduard Brynda, Pavel Májek, Tomáš Riedel
Abstract
A fibrin/heparin coating enriched with bound growth factors was developed and applied on an ePTFE vessel prosthesis. The coating exhibited excellent antithrombogenic properties and supported endothelialization of the ePTFE vessel.
Topics & Concepts
FibrinCoatingHeparinChemistryProsthesisPolymer chemistryBiomedical engineeringMaterials scienceSurgeryComposite materialMedicineBiochemistryImmunologyElectrospun Nanofibers in Biomedical ApplicationsPolymer Surface Interaction StudiesTissue Engineering and Regenerative Medicine