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The heat shock transcription factors regulate response mechanisms to abiotic stresses in plants

Yu-Xiao Wang, Jian‐Hong Xu

2025Crop Design11 citationsDOIOpen Access PDF

Abstract

Plants frequently encounter diverse abiotic stresses, including high temperature, low temperature, drought, salinity, and heavy metal contamination during their growth and development. These environmental challenges disrupt cellular homeostasis, impacting cell membrane stability, osmotic regulation, ionic composition, and leading to protein misfolding and the accumulation of reactive oxygen species (ROS). Heat shock transcription factors (HSFs) play a crucial role in plant stress response and adaptation by regulating the transcription of heat shock protein (HSP) genes and other stress-inducible genes. This process is integral to plant resilience against adverse conditions and other physiological functions. This review synthesizes the structure features, classification, regulatory mechanisms, and functional roles of plant HSFs in response to abiotic stresses such as high and low temperature, drought and salinity. Furthermore, we discuss future research directions, aiming to provide a theoretical foundation and genetic resources for enhancing crop stress tolerance through genetic improvement.

Topics & Concepts

Abiotic componentHeat shockTranscription factorCell biologyHeat shock factorHeat stressHeat shock proteinBiologyShock (circulatory)Abiotic stressEcologyHsp70GeneticsMedicineInternal medicineGeneAnimal scienceHeat shock proteins researchPlant Stress Responses and ToleranceSeed Germination and Physiology
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