NaYF<sub>4</sub>:Yb/Ho upconversion nanoprobe incorporated gold nanoparticle (AuNP) based FRET immunosensor for the “turn-on” detection of cardiac troponin I
Merin K. Abraham, Anju S. Madanan, Susan Varghese, Ali Ibrahim Shkhair, Geneva Indongo, Greeshma Rajeevan, N. S. Vijila, Sony George
Abstract
A “turn-on” NaYF 4 :Yb/Ho upconversion nanoprobe for the detection of cTnI is developed, in which AuNP is incorporated facilitating FRET mechanism. The probe exhibits appreciable sensitivity towards cTnI sensing in human serum.
Topics & Concepts
NanoprobeDetection limitTroponin IFluorescenceBiomoleculeImmunoassayNanoparticlePhoton upconversionFörster resonance energy transferChemistryMaterials scienceStreptavidinColloidal goldNanotechnologyChromatographyDopingBiotinOptoelectronicsBiochemistryAntibodyPsychiatryImmunologyPsychologyBiologyPhysicsQuantum mechanicsMyocardial infarctionGaN-based semiconductor devices and materialsGa2O3 and related materialsSemiconductor materials and devices