Mandelic acid-based spirothiazolidinones targeting M. tuberculosis: Synthesis, in vitro and in silico investigations
Muhammed Trawally, Kübra Demir-Yazıcı, Serap İpek Dingiş-Birgül, Kerem Kaya, Atilla Akdemir, Özlen Güzel-Akdemir
Topics & Concepts
AntimycobacterialINHAChemistryIn silicoMoietyMycobacterium tuberculosisMandelic acidStereochemistryIn vitroDocking (animal)Absolute configurationBiochemistryCombinatorial chemistryTuberculosisOrganic chemistryMedicineNursingGenePathologyTuberculosis Research and EpidemiologyCancer therapeutics and mechanismsSynthesis and biological activity