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Distinct mechanisms of PTEN inactivation in dogs and humans highlight convergent molecular events that drive cell division in the pathogenesis of osteosarcoma

Aaron L. Sarver, Lauren J. Mills, Kelly M. Makielski, Nuri A. Temiz, Jinhua Wang, Logan G. Spector, Subbaya Subramanian, Jaime F. Modiano

2023Cancer Genetics12 citationsDOIOpen Access PDF

Topics & Concepts

PTENBiologySomatic cellOsteosarcomaCancer researchCell cycleTumor suppressor geneLocus (genetics)GeneGeneticsPI3K/AKT/mTOR pathwayCarcinogenesisApoptosisTumors and Oncological CasesVeterinary Oncology ResearchInfectious Diseases and Mycology
Distinct mechanisms of PTEN inactivation in dogs and humans highlight convergent molecular events that drive cell division in the pathogenesis of osteosarcoma | Litcius