Litcius/Paper detail

A small-molecule VHL molecular glue degrader for cysteine dioxygenase 1

Antonin Tutter, Dennis L. Buckley, Andrei A. Golosov, Xiaolei Ma, Wei Shu, Daniel J. McKay, Véronique Darsigny, Dustin Dovala, Rohan E. J. Beckwith, Jonathan M. Solomon, Pasupuleti Rao, Lei Xu, Aleem Fazal, Andreas Lingel, Charles Wartchow, Jennifer Cobb, Amanda Hachey, Jennifer Tullai, Gregory A. Michaud

2025Nature Chemical Biology28 citationsDOI

Topics & Concepts

CysteineSmall moleculeChemistryGLUEBiochemistryCell biologyBiologyEnzymeMaterials scienceComposite materialProtein Degradation and InhibitorsPeptidase Inhibition and AnalysisAdenosine and Purinergic Signaling