Animal Models for COVID-19: Hamsters, Mouse, Ferret, Mink, Tree Shrew, and Non-human Primates
Shuyu Shou, Menghui Liu, Yang Yang, Kang Ning, Yingying Song, Dan Tan, Nannan Liu, Feifei Wang, Jing Liu, Youhua Xie
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus causing acute respiratory tract infection in humans. The virus has the characteristics of rapid transmission, long incubation period and strong pathogenicity, and has spread all over the world. Therefore, it is of great significance to select appropriate animal models for antiviral drug development and therapeutic effect evaluation. Here, we review and compare the current animal models of SARS-CoV-2.
Topics & Concepts
MinkBiologyCoronavirusVirologyTransmission (telecommunications)Incubation periodCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)HamsterRespiratory tractRespiratory systemInfectious disease (medical specialty)MedicineDiseaseIncubationPathologyAnatomyEcologyEngineeringBiochemistryMolecular biologyElectrical engineeringSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesLong-Term Effects of COVID-19