Undetectable viral RNA in oocytes from SARS-CoV-2 positive women
Montserrat Barragán, Jaime Guillén, N Martin-Palomino, Amaia Rodrı́guez, Rita Vassena
Abstract
A central concern for the safe provision of ART during the current coronavirus disease 2019 (COVID-19) pandemic is the possibility of vertical transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection through gametes and preimplantation embryos. Unfortunately, data on SARS-CoV-2 viral presence in oocytes of infected individuals are not available to date. We describe the case of two women who underwent controlled ovarian stimulation and tested positive to SARS-CoV-2 infection by PCR on the day of oocyte collection. The viral RNA for gene N was undetectable in all the oocytes analyzed from the two women.
Topics & Concepts
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyCoronavirus disease 2019 (COVID-19)RNA2019-20 coronavirus outbreakBiologyBetacoronavirusMedicineGeneticsInternal medicineGeneOutbreakDiseaseInfectious disease (medical specialty)COVID-19 Impact on ReproductionCOVID-19 and healthcare impactsSARS-CoV-2 and COVID-19 Research