Lineage Divergence and Vector-Specific Adaptation Have Driven Chikungunya Virus onto Multiple Adaptive Landscapes
Rubing Chen, Jessica A. Plante, Kenneth S. Plante, Ruimei Yun, Divya Shinde, Jianying Liu, Sherry Haller, Suchetana Mukhopadhyay, Scott C. Weaver
Abstract
Since its introduction into the Caribbean in October 2013, CHIKV has rapidly spread to almost the entire neotropical region. However, its potential to further spread globally, including into more temperate climates, depends in part on its ability to be transmitted efficiently by Aedes albopictus , which can survive colder winters than A. aegypti .
Topics & Concepts
Lineage (genetic)ChikungunyaBiologyAdaptation (eye)Aedes albopictusAedes aegyptiInfectivityEvolutionary biologyEpistasisVirusVector (molecular biology)AedesGeneticsMutationTransmission (telecommunications)VirologyHost (biology)Divergence (linguistics)ArbovirusGenePhylogenetic treeZoologyAlphavirusPhylogeneticsEnvelope (radar)Viral evolutionAlphavirus infectionNicheCladeMosquito-borne diseases and controlZoonotic diseases and public healthDengue and Mosquito Control Research