Evidence that tissue recoil in the early <i>Drosophila</i> embryo is a passive not active process
Amanda Nicole Goldner, Salena M. Fessehaye, Nataly Rodriguez, Kelly Mapes, Miriam Osterfield, Konstantin Doubrovinski
Abstract
Techniques to examine the contribution of specific proteins to tissue mechanical properties are extremely limited. Here, Goldner et al. develop two complementary techniques for rapid protein depletion combined with mechanical measurements and show that myosin activity is dispensable for tissue elasticity.
Topics & Concepts
BiologyMyosinCell biologyEmbryoElastic recoilDrosophila melanogasterElasticity (physics)BiophysicsGeneticsGeneLungMaterials sciencePhilosophyComposite materialLinguisticsCellular Mechanics and InteractionsCardiomyopathy and Myosin StudiesSilk-based biomaterials and applications