Hydride Transfer-Initiated Cross-Dehydrogenative Coupling Reaction to Access Nine-Membered Rings
Xiao‐De An, Da-Ying Shao, Bin Qiu, Jian Xiao
Abstract
An unprecedented hydride transfer-triggered cross-dehydrogenative coupling of two C(sp 3 )–H bonds to target nine-membered rings has been developed. Salient features of this methodology include atom and step economy and metal-free and redox-neutral conditions, with water as the byproduct and proceeding well even with decomposed aldehydes.
Topics & Concepts
ChemistryHydrideCoupling (piping)RedoxTransfer (computing)Coupling reactionAtom (system on chip)PhotochemistryMetalCombinatorial chemistryPolymer chemistryOrganic chemistryCatalysisMetallurgyMaterials scienceParallel computingComputer scienceEmbedded systemCatalytic C–H Functionalization MethodsSynthesis and Catalytic ReactionsCatalytic Cross-Coupling Reactions