ADAMTS9-AS2 regulates PPP1R12B by adsorbing miR-196b-5p and affects cell cycle-related signaling pathways inhibiting the malignant process of esophageal cancer
Zhao Chen, Zhao Chen, Weijian Tang, Weiwen Ye, Lijiang Song, Zhoumiao Chen, Zhoumiao Chen
Abstract
through miR-196b-5p/PPP1R12B/cell cycle signaling pathway axis. ADAMTS9-AS2 downregulated PPP1R12B by adsorbing miR-196b-5p, so as to regulate the cell cycle signaling pathway to inhibit EC malignant progression.
Topics & Concepts
BiologyCell cycleCarcinogenesisCyclin-dependent kinase 1microRNACancer researchFlow cytometryCellCell growthCell cycle checkpointCell biologyCancerMolecular biologyGeneBiochemistryGeneticsCancer-related molecular mechanisms researchRNA modifications and cancerMicroRNA in disease regulation