Targeting matrix metalloproteinases by E3 ubiquitin ligases as a way to regulate the tumor microenvironment for cancer therapy
Jinxin Liu, Ting Chen, Shizhe Li, Wenjun Liu, Peter Wang, Guanning Shang
Topics & Concepts
Matrix metalloproteinaseCarcinogenesisTumor microenvironmentUbiquitinExtracellular matrixCancer researchCancerUbiquitin ligaseBiologyTumor progressionCell biologyChemistryBiochemistryTumor cellsGeneticsGenePeptidase Inhibition and AnalysisProtease and Inhibitor MechanismsUbiquitin and proteasome pathways