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Maintaining manganese in tumor to activate cGAS-STING pathway evokes a robust abscopal anti-tumor effect

Chao Wang, Zhaoyi Sun, Chenxuan Zhao, Zhewei Zhang, Haoran Wang, Yang Liu, Yunfei Guo, Bingtao Zhang, Lihong Gu, Yue Yu, Yiqiao Hu, Jinhui Wu

2021Journal of Controlled Release136 citationsDOI

Topics & Concepts

CytosolChemistryImmunityDNACancer researchDNA damageImmune systemCell biologyStimulator of interferon genesApoptosisBiochemistryBiologyImmunologyEnzymeinterferon and immune responsesRNA modifications and cancerImmune Response and Inflammation
Maintaining manganese in tumor to activate cGAS-STING pathway evokes a robust abscopal anti-tumor effect | Litcius