Copper-catalyzed multiple oxidation and cycloaddition of aryl–alkyl ketones (alcohols) for the synthesis of 4-acyl- and 4-diketo-1,2,3-triazoles
Liang‐Feng Huang, Lei Zheng, Zhong‐Zhen Zhou, Yunfeng Chen
Abstract
A Cu/TEMPO-catalyzed multiple oxidation and cyclization reaction from readily-available ketones (or alcohols) and organic azides has been developed.
Topics & Concepts
CycloadditionChemistryDehydrogenationAlkylCatalysisArylOrganic chemistrySolventTandemCombinatorial chemistryMaterials scienceComposite materialClick Chemistry and ApplicationsCatalytic C–H Functionalization MethodsSynthesis and Biological Evaluation