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An overview of the applications of chiral phosphoric acid organocatalysts in enantioselective additions to CO and CN bonds

Xabier del Corte, Edorta Martínez de Marigorta, Francisco Palácios, Javier Vicario, Aitor Maestro

2022Organic Chemistry Frontiers54 citationsDOIOpen Access PDF

Abstract

Since 2004, chiral phosphoric acids (CPAs) have emerged as highyl efficient organocatalysts, providing excellent results in a wide reaction scope. In this review, the applications of CPA for enantioselective additions to CO and CN bonds are covered.

Topics & Concepts

Enantioselective synthesisPhosphoric acidChemistryOrganocatalysisScope (computer science)Organic chemistryCatalysisCombinatorial chemistryComputer scienceProgramming languageAsymmetric Synthesis and CatalysisAsymmetric Hydrogenation and CatalysisChemical Synthesis and Analysis
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