Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration
Dylan V. Neel, Himanish Basu, Georgia Gunner, Matthew Bergstresser, Richard M. Giadone, Haeji Chung, Rui Miao, Vicky Chou, Eliza M. Brody, Xin Jiang, Edward B. Lee, Michelle Watts, Christine Marques, Aaron Held, Brian J. Wainger, Clotilde Lagier‐Tourenne, Yong‐Jie Zhang, Leonard Petrucelli, Tracy L. Young‐Pearse, Alice Chen‐Plotkin, Lee L. Rubin, Judy Lieberman, Isaac M. Chiu
Topics & Concepts
NeurodegenerationMitochondrionAxonBiologyAmyotrophic lateral sclerosisNeuroscienceNeuriteCell biologyGene knockdownApoptosisPathologyMedicineGeneticsIn vitroDiseaseAlzheimer's disease research and treatmentsAmyotrophic Lateral Sclerosis ResearchNeurological diseases and metabolism