Low-Valent Tungsten-Catalyzed Controllable Oxidative Dehydrogenative Coupling of Anilines
Xingwei Cai, Shen Yang, Wei Li, Wentao Zhan, Fanjun Zhang, Chen Xu, Heng Song
Abstract
Herein, we have developed an efficient tungsten-catalyzed homogeneous system for oxidative dehydrogenative coupling of anilines to selectively produce various azoaromatics and azoxyaromatics as well as 2-substituted indolone N-oxides by simply regulating the reaction solvent with peroxide as a terminal oxidant under additive-free conditions. These findings provide an experimental framework for exploring tungsten catalysis in organic synthesis and offer an efficient and convenient tactic for the selective oxidation of anilines.
Topics & Concepts
ChemistryCatalysisOxidative phosphorylationTungstenOxidative coupling of methaneHomogeneousCombinatorial chemistryPeroxideSolventCoupling (piping)Hydrogen peroxideHomogeneous catalysisOrganic chemistryMaterials scienceThermodynamicsMetallurgyBiochemistryPhysicsCatalytic C–H Functionalization MethodsPolyoxometalates: Synthesis and ApplicationsSynthesis and Catalytic Reactions