GPX4: The hub of lipid oxidation, ferroptosis, disease and treatment

Yi Liu, Yicong Wan, Yi Jiang, Lin Zhang, Wenjun Cheng

2023Biochimica et Biophysica Acta (BBA) - Reviews on Cancer484 citationsDOI

Topics & Concepts

GPX4DiseaseMechanism (biology)RegulatorCarcinogenesisLipid peroxidationProgrammed cell deathLipid metabolismPhospholipid-hydroperoxide glutathione peroxidaseCell biologyCancer researchGlutathione peroxidaseCancerBiologyAntioxidantBiochemistryMedicineApoptosisCatalaseInternal medicineGeneticsGeneEpistemologyPhilosophyFerroptosis and cancer prognosisGlutathione Transferases and PolymorphismsCancer, Lipids, and Metabolism