PDGFR-β+ fibroblasts deteriorate survival in human solid tumors: a meta-analysis
Guoming Hu, Liming Huang, Kefang Zhong, Liwei Meng, Feng Xu, Shimin Wang, Tao Zhang
Abstract
fibroblast infiltration deteriorates survival in human solid tumors especially in NSCLC, breast and pancreatic cancer. Hence, they may offer a practicable prognostic biomarker and a potential therapeutic strategy for these patients.
Topics & Concepts
Cancer researchPlatelet-derived growth factor receptorOncologyInternal medicineMedicineReceptorGrowth factorFibroblast Growth Factor ResearchCancer, Hypoxia, and MetabolismImmune cells in cancer