Role of damaged mitochondrial transfer in alpha-particle generator <sup>212</sup>Pb radiation-induced bystander effect
Mengdie Yang, Lusheng Wang, Shanshan Qin, Xiongxin Dai, J. G. Li, Liwei An, Lijuan Song, Jie Gao, Zongtai Han, Fei Yu
Abstract
Pb and, more importantly, elucidates the role of damaged mitochondrial transfer in alpha-particle RIBE. These findings provide a novel theoretical mechanism for the antitumor effects of alpha-particles and expand the clinical application prospects of TAT.
Topics & Concepts
Bystander effectAlpha particleAlpha (finance)RadiochemistryPhysicsRadiationAtomic physicsChemistryNuclear physicsBiophysicsMedicineBiologyImmunologyConstruct validityNursingPatient satisfactionRadiation Therapy and DosimetryAdvanced Radiotherapy TechniquesEffects of Radiation Exposure