Epigenetic reader BRD4 supports mycobacterial pathogenesis by co-modulating host lipophagy and angiogenesis
Tanushree Mukherjee, Bharat Bhatt, Praveen Prakhar, Gaurav Kumar Lohia, Raju S Rajmani, Kithiganahalli Narayanaswamy Balaji
Abstract
; PECAM1: platelet and endothelial cell adhesion molecule 1; SQSTM1/p62: sequestosome 1; TB: tuberculosis; THBS1: thrombospondin 1; VEGF: vascular endothelial growth factor.
Topics & Concepts
AutophagyBRD4BiologyATG5Gene knockdownCancer researchLipid dropletEpigeneticsHistoneAngiogenesisCell biologyMycobacterium tuberculosisBromodomainCell cultureTuberculosisMedicineGeneticsApoptosisGenePathologyProtein Degradation and InhibitorsHIV Research and TreatmentImmune Cell Function and Interaction