Characterization of primary mouse hepatocyte spheroids as a model system to support investigations of drug-induced liver injury
Manisha Nautiyal, Rani J. Qasem, John K. Fallon, Kristina Wolf, Jingli Liu, Darlene Dixon, Philip C. Smith, Merrie Mosedale
Topics & Concepts
SpheroidHepatocyteAlbuminLiver injuryDrugBiologyPharmacologyAcetaminophenCell biologyCell cultureBiochemistryIn vitroGeneticsLiver physiology and pathologyPharmacogenetics and Drug MetabolismDrug-Induced Hepatotoxicity and Protection