Expression of Novel L-Leucine Dehydrogenase and High-Level Production of L-Tert-Leucine Catalyzed by Engineered Escherichia coli
Yuanyuan Jia, Yu-Li Xie, Lu-Lu Yang, Hongling Shi, Yunfeng Lu, Si-Pu Zhang, Cun‐Duo Tang, Lunguang Yao, Yunchao Kan
Abstract
Graphical Abstract Genome mining of Leucine dehydrogenase and one-pot synthesis of L -tert-leucine from trimethylpyruvic acid.
Topics & Concepts
LeucineEscherichia coliChemistryBiochemistryDehydrogenaseEnzymeAmino acidGeneEnzyme Structure and FunctionEnzyme Catalysis and ImmobilizationMetabolism and Genetic Disorders