Oxygen-independent free radical generation mediated by core-shell magnetic nanocomposites synergizes with immune checkpoint blockade for effective primary and metastatic tumor treatment
Jincheng Guo, Qiao An, Mengyu Guo, Yating Xiao, Bo Li, Fene Gao, Yuqing Wang, Jiayang Li, Yaling Wang, Ying Liu, Huan Meng, Jia Guo, Jing Liu
Topics & Concepts
Cancer researchImmune checkpointImmune systemMetastasisPrimary tumorTumor hypoxiaTumor microenvironmentImmunotherapyBlockadePhotodynamic therapyImmunogenic cell deathMedicineChemistryImmunologyCancerReceptorInternal medicineRadiation therapyOrganic chemistryNanoplatforms for cancer theranosticsImmune cells in cancerCancer, Hypoxia, and Metabolism