Design and synthesis of dual inhibitors targeting snail and histone deacetylase for the treatment of solid tumour cancer
Cui Hao, Jingkun Huang, Lei Yan, Quanwei Chen, Zan Hu, Jiaqi Niu, Ran Wei, Yang Kang, Hongmei Li, Tao Lu, Yong Zhu, Yatian Huang
Topics & Concepts
SnailHDAC1ChemistryHistone deacetylaseAcetylationDocking (animal)IC50Cancer cellPharmacologyHistoneCancer researchCancerBiochemistryIn vitroBiologyMedicineGeneticsGeneEcologyNursingHistone Deacetylase Inhibitors ResearchPeptidase Inhibition and AnalysisCholinesterase and Neurodegenerative Diseases