Carrier-free quercetin nanomedicine blocks NLRP3 deubiquitination and TXNIP recruitment for Parkinson’s disease therapy
Dongju Zhao, Chao Tian, Meng Cheng, Fan Yang, Chunxiao Tian, Yining Liu, Ziyao Chen, Gaoju Pang, Hui Shen, Jin Woo Chang, Yan Dou
Topics & Concepts
InflammasomeNeurodegenerationNeuroinflammationDopaminergicNeuroscienceTXNIPPharmacologyParkinson's diseaseNanomedicineMedicineDopamineChemistryBiologyDiseaseImmunologyInflammationNanotechnologyOxidative stressInternal medicineNanoparticleMaterials scienceThioredoxinNeuroinflammation and Neurodegeneration MechanismsLysosomal Storage Disorders ResearchAutophagy in Disease and Therapy