Battling COVID-19: using old weapons for a new enemy
Rohit Kumar, Nitin Gupta, Parul Kodan, Ankit Mittal, Manish Soneja, Naveet Wig
Abstract
Coronavirus disease-19 (COVID-19) has reached pandemic proportions. Most of the drugs that are being tried for the treatment have not been evaluated in any randomized controlled trials. The purpose of this review was to summarize the in-vitro and in-vivo efficacy of these drugs on Severe Acute Respiratory Syndrome (SARS-CoV-2) and related viruses (SARS and Middle East Respiratory Syndrome) and evaluate their potential for re-purposing them in the management of COVID-19.
Topics & Concepts
Coronavirus disease 2019 (COVID-19)PandemicMiddle East respiratory syndromeSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakMiddle East respiratory syndrome coronavirusCoronavirusMedicineBetacoronavirusVirologyOutbreakIntensive care medicineDiseaseInfectious disease (medical specialty)Internal medicineCOVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchLong-Term Effects of COVID-19