Complete 1H and 13C NMR spectral assignment of d-glucofuranose
Elin Alexandersson, Gustav Nestor
Abstract
Although d-glucose is the most common sugar in nature, only a few NMR studies have focused on its minor furanose forms, and they have been limited to the anomeric position. Here, complete 1H and 13C NMR spectral analysis of α- and β-d-glucofuranose was performed, including signal assignment, chemical shifts, and coupling constants. Selective and non-selective 1D and 2D NMR experiments were used for the analysis, complemented by spin simulations and iterative spectral analysis.
Topics & Concepts
ChemistryCarbon-13 NMRAnomerChemical shiftSpectral analysisFuranoseProton NMRComputational chemistryStereochemistryOrganic chemistryPhysical chemistrySpectroscopyPhysicsQuantum mechanicsRing (chemistry)Diet, Metabolism, and DiseaseCarbohydrate Chemistry and SynthesisBiochemical Analysis and Sensing Techniques