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Increased Technology Use Associated With Lower A1C in a Large Pediatric Clinical Population

G. Todd Alonso, Taylor M. Triolo, Halis Kaan Aktürk, MEGHAN E. PAULEY, Marisa Sobczak, Gregory P. Forlenza, Casey Sakamoto, Laura Pyle, Brigitte I. Frohnert

2023Diabetes Care28 citationsDOIOpen Access PDF

Abstract

OBJECTIVE: While continuous glucose monitors (CGMs), insulin pumps, and hybrid closed-loop (HCL) systems each improve glycemic control in type 1 diabetes, it is unclear how the use of these technologies impacts real-world pediatric care. RESEARCH DESIGN AND METHODS: We found 1,455 patients aged <22 years, with type 1 diabetes duration >3 months, and who had data from a single center in between both 2016-2017 (n = 2,827) and 2020-2021 (n = 2,731). Patients were grouped by multiple daily injections or insulin pump, with or without an HCL system, and using a blood glucose monitor or CGM. Glycemic control was compared using linear mixed-effects models adjusting for age, diabetes duration, and race/ethnicity. RESULTS: CGM use increased from 32.9 to 75.3%, and HCL use increased from 0.3 to 27.9%. Overall A1C decreased from 8.9 to 8.6% (P < 0.0001). CONCLUSIONS: Adoption of CGM and HCL was associated with decreased A1C, suggesting promotion of these technologies may yield glycemic benefits.

Topics & Concepts

MedicineGlycemicType 1 diabetesInsulin pumpDiabetes mellitusContinuous glucose monitoringInsulinPopulationInternal medicineIntensive care medicineEndocrinologyEnvironmental healthDiabetes Management and ResearchHyperglycemia and glycemic control in critically ill and hospitalized patientsPancreatic function and diabetes
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